CVE-2026-100843
Received Received - Intake

Remote Code Execution in MONAI via Unsafe Pickle Deserialization

Vulnerability report for CVE-2026-100843, including description, CVSS score, EPSS score, affected products, exploitability, helpful resources, and attack-flow context.

Publication date: 2026-09-27

Last updated on: 2026-09-27

Assigner: VulnCheck

Description

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

CVSS Scores

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Meta Information

Published
2026-09-27
Last Modified
2026-09-27
Generated
2026-09-27
AI Q&A
2026-09-27
EPSS Evaluated
N/A
NVD
EUVD

Affected Vendors & Products

Showing 2 associated CPEs
Vendor Product Version / Range
monai monai to 1.6.0 (exc)
project_monai monai to 1.6.0 (exc)

Helpful Resources

Exploitability

CWE
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KEV
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CWE ID Description
CWE-502 The product deserializes untrusted data without sufficiently ensuring that the resulting data will be valid.

Attack-Flow Graph

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Executive Summary

CVE-2026-100843 is a remote code execution vulnerability in MONAI versions before 1.6.0. It exists in the algo_from_pickle() function due to unsafe use of pickle.loads() in monai/auto3dseg/utils.py. Attackers can exploit this by crafting malicious pickle files that execute arbitrary system commands when deserialized.

Detection Guidance

To detect this vulnerability, check if MONAI versions before 1.6.0 are installed by running commands like 'pip show monai' or 'conda list monai' to verify the version. Inspect files in the MONAI package for the vulnerable function 'algo_from_pickle()' in 'monai/auto3dseg/utils.py'.

Impact Analysis

This vulnerability allows attackers to execute arbitrary system commands on systems running vulnerable MONAI versions. If you use MONAI in workflows, especially with untrusted model checkpoints, an attacker could compromise your system, steal data, or disrupt operations. Upgrading to version 1.6.0 or later mitigates this risk.

Compliance Impact

This vulnerability could lead to unauthorized code execution on systems processing sensitive data, potentially violating GDPR's integrity and confidentiality requirements (Article 32) and HIPAA's security rule (45 CFR 164.308) by allowing unauthorized access to protected health information.

Mitigation Strategies

Immediately upgrade MONAI to version 1.6.0 or later using 'pip install --upgrade monai' or 'conda update monai'. Avoid processing untrusted pickle files in MONAI workflows until the upgrade is complete.

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